葛根
葛根
异黄酮素
化学
萃取(化学)
洛巴塔
成分
食品科学
传统医学
葛根素
色谱法
生物化学
医学
中医药
病理
替代医学
作者
Andrei Mocan,Simone Carradori,Marcello Locatelli,Daniela Secci,Stefania Cesa,Adriano Mollica,Simona Riga,Andrea Angeli,Christian Celia,Luisa Di Marzio
标识
DOI:10.1016/j.fct.2017.08.009
摘要
Kudzu, the dried root of an important edible plant (Pueraria lobata), is used in Traditional Chinese Medicine for the important nutritional value strictly related to its isoflavone derivatives. These compounds characterize the quality of kudzu contained in different preparations, as pharmaceutical ingredient as well as dietary/food supplement (e.g. starch). The optimization of the isoflavones recovery, monitored by HPLC-PDA, through different innovative and conventional extraction techniques, e.g. microwave-assisted, ultrasound-assisted and conventional extraction, represented a suitable challenge in food industry and natural products evaluation. The impact on the isoflavone extraction by using an ionic liquid-assisted procedure was also considered. Furthermore, the inhibitory activity of the most representative isoflavones, isolated from kudzu, was evaluated using four isoforms (I, II, IX and XII) of human carbonic anhydrase (hCA) due to their role in several physiopathological processes.
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