Sperm DNA fragmentation index and male infertility

Numerous cases of men infertility are caused by sperm DNA damage, which routine semen quality examines fail to identify. Aim: To evaluate the relationship between sperm fragmentation index with semen parameters, age, Body Mass Index, smoking and infertility duration. Materials and Methods: A total of 88 cases underwent routine semen analysis along with sperm fragmentation index using the Sperm Chromatin Dispersion Test. Sperm parameters were evaluated according to the World Health Organization guidelines. Results: This study indicated that 64% of males had high DNA fragmentation. No correlation was found between DFI, age and BMI. While, the threat of presenting abnormal levels of DNA fragmentation increased with infertility duration.