化学
微乳液
角质层
透皮
共晶体系
渗透(战争)
薄荷醇
溶剂
基础油
深共晶溶剂
色谱法
化学工程
有机化学
药理学
肺表面活性物质
复合材料
材料科学
病理
工程类
医学
合金
生物化学
运筹学
扫描电子显微镜
作者
Yuma Hamada,Mina Saeedi
出处
期刊:Chemistry Letters
[The Chemical Society of Japan]
日期:2022-09-05
卷期号:51 (9): 894-897
被引量:2
摘要
We investigated the structural properties of microemulsions (MEs) dispersed in oil base including hydrophobic deep eutectic solvents (DESs) and their skin permeabilities. The results showed that the addition of DESs can improve the skin penetration of monodispersed MEs by disturbing the lipid structures in the stratum corneum. Further addition of DESs caused the structural transition of MEs from a sphere to a cylinder and a bicontinuous system and decreased reduced skin penetration. We investigated the structural properties of microemulsions (MEs) dispersed in oil base including hydrophobic deep eutectic solvents (DESs) and their skin permeabilities. DES caused the structural transition of MEs from a sphere to a cylinder and to a bicontinuous system. MEs dispersed in the solvent containing a moderate amount of DES, which formed a cylindrical structure, penetrated the skin most.
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