Pharmacological effects of D‐Pinitol – A comprehensive review

Journal of Food BiochemistryEarly View e14282 REVIEW Pharmacological effects of D-Pinitol – A comprehensive review Anandakumar Pandi, Corresponding Author Anandakumar Pandi anand.biochemistry@aiimsdeoghar.edu.in Department of Biochemistry, All India Institute of Medical Sciences (AIIMS)-Deoghar, Deoghar, Jharkhand, India Correspondence Anandakumar Pandi, Department of Biochemistry, AIIMS Deoghar, Deoghar, Jharkhand 814 142, India. Email: anand.biochemistry@aiimsdeoghar.edu.inSearch for more papers by this authorKamaraj Sattu, Kamaraj Sattu Department of Biotechnology, Periyar University, PG Extension centre, Dharmapuri, Tamilnadu, IndiaSearch for more papers by this authorVanitha M. Kalappan, Vanitha M. Kalappan Formerly, Department of Medical Biochemistry, University of Madras, Taramani campus, Chennai, Tamilnadu, IndiaSearch for more papers by this authorVanita Lal, Vanita Lal Department of Biochemistry, All India Institute of Medical Sciences (AIIMS)-Deoghar, Deoghar, Jharkhand, IndiaSearch for more papers by this authorSeshadri R. Varikasuvu, Seshadri R. Varikasuvu Department of Biochemistry, All India Institute of Medical Sciences (AIIMS)-Deoghar, Deoghar, Jharkhand, IndiaSearch for more papers by this authorAnirban Ganguly, Anirban Ganguly orcid.org/0000-0002-5007-7116 Department of Biochemistry, All India Institute of Medical Sciences (AIIMS)-Deoghar, Deoghar, Jharkhand, IndiaSearch for more papers by this authorJitender Prasad, Jitender Prasad Department of Biochemistry, All India Institute of Medical Sciences (AIIMS)-Deoghar, Deoghar, Jharkhand, IndiaSearch for more papers by this author Anandakumar Pandi, Corresponding Author Anandakumar Pandi anand.biochemistry@aiimsdeoghar.edu.in Department of Biochemistry, All India Institute of Medical Sciences (AIIMS)-Deoghar, Deoghar, Jharkhand, India Correspondence Anandakumar Pandi, Department of Biochemistry, AIIMS Deoghar, Deoghar, Jharkhand 814 142, India. Email: anand.biochemistry@aiimsdeoghar.edu.inSearch for more papers by this authorKamaraj Sattu, Kamaraj Sattu Department of Biotechnology, Periyar University, PG Extension centre, Dharmapuri, Tamilnadu, IndiaSearch for more papers by this authorVanitha M. Kalappan, Vanitha M. Kalappan Formerly, Department of Medical Biochemistry, University of Madras, Taramani campus, Chennai, Tamilnadu, IndiaSearch for more papers by this authorVanita Lal, Vanita Lal Department of Biochemistry, All India Institute of Medical Sciences (AIIMS)-Deoghar, Deoghar, Jharkhand, IndiaSearch for more papers by this authorSeshadri R. Varikasuvu, Seshadri R. Varikasuvu Department of Biochemistry, All India Institute of Medical Sciences (AIIMS)-Deoghar, Deoghar, Jharkhand, IndiaSearch for more papers by this authorAnirban Ganguly, Anirban Ganguly orcid.org/0000-0002-5007-7116 Department of Biochemistry, All India Institute of Medical Sciences (AIIMS)-Deoghar, Deoghar, Jharkhand, IndiaSearch for more papers by this authorJitender Prasad, Jitender Prasad Department of Biochemistry, All India Institute of Medical Sciences (AIIMS)-Deoghar, Deoghar, Jharkhand, IndiaSearch for more papers by this author First published: 23 June 2022 https://doi.org/10.1111/jfbc.14282Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abstract In recent years, the application of phytochemicals to prevent or treat diseases has received greater attention. These phytochemicals have little or no toxicity against healthy tissues and are thus considered as ideal compounds. An impressive number of modern drugs are obtained from natural sources based on their traditional value. D-Pinitol is a natural compound that is derived from soy and soy products. It is a potentially active molecule that belongs to the class of inositols. D-pinitol has been pharmacologically evaluated for its potent antioxidant, anti-diabetic, anti-inflammatory, anti-cancer, hepatoprotective, cardioprotective, renoprotective, neuroprotective, immunosuppressive, and anti-osteoporotic efficacies. This review is an attempt to validate the plausible pharmacological effects of D-pinitol using various in vivo and in vitro studies. Practical implications The consumption of plant-based products has been significantly increased all over the world. The active phytochemicals that are found in plants are stated to have numerous health promoting functions for the treatment of diabetes, cancer, inflammation, cardiac diseases, liver dysfunction, and many other. D-Pinitol is abundantly present in soybeans that possess notable therapeutic activities. Understanding the effects of D-Pinitol would potentially help in applying this compound in clinical research for the treatment of different disorders. CONFLICT OF INTEREST The authors declare that they have no conflict of interest. Open Research DATA AVAILABILITY STATEMENT No data are available. Early ViewOnline Version of Record before inclusion in an issuee14282 RelatedInformation