对映选择合成
离子
还原(数学)
催化作用
化学
组合化学
反应中间体
有机化学
数学
几何学
作者
Masahiro Terada,T. Yamanaka,Yasunori Toda
标识
DOI:10.1002/chem.201302486
摘要
Anionic! Novel chiral anion catalysis of the enantioselective 1,4-reduction of the 1-benzopyrylium ion by a chiral phosphoric acid was accomplished with a Hantzsch ester as the reducing agent. The enantioselective reduction established is composed of a two-step consecutive transformation involving stereoablative loss of the hydroxy group from racemic 2H-chromen-2-ol derivatives to generate the achiral 1-benzopyrylium ion as a reactive key intermediate.
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