两性霉素B
异硫氰酸荧光素
抗真菌
碳纳米管
异硫氰酸盐
药物输送
纳米技术
抗真菌药
荧光素
化学
材料科学
生物化学
微生物学
荧光
生物
物理
量子力学
作者
Wei Wu,Sébastien Wieckowski,Giorgia Pastorin,Monica Benincasa,Cédric Klumpp,Jean‐Paul Briand,Renato Gennaro,Maurizio Prato,Alberto Bianco
标识
DOI:10.1002/anie.200501613
摘要
Tasty tubes: Multiwalled carbon nanotubes functionalized with fluorescein isothiocyanate and amphotericin B (AmB) have been shown to be rapidly internalized by mammalian cells (see picture) without the toxic effects typically displayed upon treatment with AmB. Furthermore, the modified drug exhibits a higher antifungal activity than native AmB.
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