麻疹
泊松回归
入射(几何)
中国
置信区间
人口学
免疫
医学
流行病学
相对风险
环境卫生
地理
人口
免疫学
接种疫苗
数学
内科学
抗体
考古
社会学
几何学
作者
Abram L. Wagner,Ying Zhang,Bhramar Mukherjee,Yaxing Ding,Eden V. Wells,Matthew L. Boulton
标识
DOI:10.1016/j.ijid.2016.03.005
摘要
China has repeatedly used supplemental immunization activities (SIAs) to work towards measles elimination, but it is unknown if the SIAs are reaching non-locals - migrants from rural to urban areas. This study characterized temporal trends in measles incidence by local and non-local residency and evaluated the impact of SIAs on measles incidence in Tianjin, China.Daily measles case-counts were tabulated separately by residency. These two datasets were combined so that each day had two observations. Poisson regression was conducted using generalized estimating equations with an exchangeable working correlation structure to estimate rate ratios (RRs).There were 12465 measles cases in Tianjin over the 10-year period. The rate of measles was higher in non-locals than locals before the 2008 SIA (RR 3.60, 95% confidence interval (CI) 3.27-3.96), but this attenuated to a RR of 1.22 between the 2008 and 2010 SIAs (95% CI 1.02-1.45). Following the 2010 SIA, non-locals had a lower rate of measles (RR 0.78, 95% CI 0.69-0.87).The disparity in measles incidence between locals and non-locals was reduced following two SIAs. Sustained public health interventions will be needed to maintain low measles incidence among non-locals given the ongoing migration of people throughout China.
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