驴子
生物
亚洲马
繁殖
进化生物学
遗传变异
克莱德
人口
牲畜
遗传学
选择(遗传算法)
基因组
基因
系统发育树
生态学
社会学
人口学
人工智能
计算机科学
作者
Jiafei Shen,Jingling Li,Xuelei Dai,Mei Li,Gang Wang,Ningbo Chen,Hong Chen,Chuzhao Lei,Ruihua Dang
标识
DOI:10.1016/j.jgg.2021.05.012
摘要
Donkey (Equus asinus) is an important livestock animal in China because of its draft and medicinal value. After a long period of natural and artificial selection, the variety and phenotype of donkeys have become abundant. We clarified the genetic and demographic characteristics of Chinese domestic donkeys and the selection pressures by analyzing 78 whole genomes from 12 breeds. According to population structure, most Chinese domestic donkeys showed a dominant ancestral type. However, the Chinese donkeys still represented a significant geographical distribution trend. In the selective sweep, gene annotation, functional enrichment, and differential expression analyses between large and small donkey groups, we identified selective signals, including NCAPG and LCORL, which are related to rapid growth and large body size. Our findings elucidate the evolutionary history and formation of different donkey breeds and provide theoretical insights into the genetic mechanism underlying breed characteristics and molecular breeding programs of donkey clades.
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