The correlation between atrial natriuretic peptide and echocardiogram parameters of cardiac function in heart failure

Objective:To discuss the relationship between atrial natriuretic peptide(ANP) and the cardiac function in patients with heart failure. Methods: The plasma levels of ANP were tested by specific radio -immunoassay and the left cardiac function parameters were obtained by echocardiogram in different grade patients with heart failure. Results: The plasma levels of ANP elevated with the worsening of heart failure (NYHA Classification). The plasma levels of ANP were negatively correlated with left ventricle ejection fraction (LVEF)and fraction shortering % (D%) and positively correlated with left ventricle end - systolic volumeml (LVSd) and left ventricle end - diastolic volumeml (LVDd). Conclusion: In progressing of heart failure, ANP has a close correlation with the cardiac function and echocardiogram parameters of cardiac function in heart failure.