Effect of the Therapy of Budesonide Inhalation Associated with Tiotropium Bromide Inhalation on COPD

Objective: To observe the effect of the therapy of budesonide inhalation associated with tiotropium bromide inhalation on COPD.Method: 107 patients diagnosed with COPD between October,2009 and May,2010 in our hospital into quickly aggravating subgroup and stable subgroup.Patients in each subgroup were randomly divided into two settings,one setting received the therapy of budesonide inhalation associated with tiotropium bromide inhalation,the other one receiving only the therapy of budesonide inhalation as a control.At the beginning and after 7 days curing,We both made comparison of FEV1/FVC,blood gas analysis and changes in dyspnea grade between two settings.Result: Before the curing started,we found no Significant difference between two settings in each subgroup(P0.05),but after 7 days curing,the significant difference appeared(P0.05).Conclusion: Pulmonary function and life quality of the COPD patients can be effectively improved after therapy of budesonide inhalation associated with tiotropium bromide inhalation.