医学
炎症性肠病
内科学
胃肠病学
克罗恩病
核医学
疾病
碘
计算机断层摄影术
外科
冶金
材料科学
作者
Bari Dane,Ahmad Garada,Thomas O’Donnell,Sam S. Chang,Alec J. Megibow
标识
DOI:10.1097/rct.0000000000001135
摘要
Objective The objective of this study was to determine if dual-energy computed tomography enterography (DECTE)–obtained iodine density can predict medical management change or surgery in Crohn disease patients. Methods The most active-appearing bowel segment on DECTE in 21 Crohn disease patients was retrospectively interrogated with prototype software determining the percentage of bowel wall (I) in specified ranges. Patients were categorized into 3 groups after DECTE: (1) no management change, (2) outpatient medication change, and (3) inpatient admission or surgery. Crohn's disease activity index was calculated. Group 3's percentage iodine density of >3 mg/mL and Crohn's disease activity index were compared with group 1/2. Crohn's disease activity index and percentage iodine density of >2 mg/mL were compared for groups 2/3 versus group 1 patients. Results There were 5 group 1, 6 group 2, and 10 group 3 patients. Group 3 patients had higher frequency of iodine density >3 mg/mL (27%) compared with groups 1/2 patients (12.6%) ( P < 0.05). Crohn's disease activity index was similar ( P = 0.98). Groups 2/3 patients had 60.5% iodine density of >2 mg/mL, whereas group 1 patients had 31.7% iodine density of >2 mg/mL ( P < 0.05). Crohn's disease activity index was similar ( P = 0.12). Conclusions Iodine density from DECTE may predict medical or surgical Crohn disease management.
科研通智能强力驱动
Strongly Powered by AbleSci AI