Biocatalytic Asymmetric Ring-Opening of meso-Epoxides to Enantiopure Cyclic trans-β-Amino Alcohols Involving a Key Amine Transaminase

Chiral cyclic β-amino alcohols are vital building blocks for the synthesis of numerous pharmaceuticals and bioactive molecules. Asymmetric ring-opening of cyclic meso-epoxides is a straightforward and appealing method for their...