2,3′‐Bisindole Synthesis fromo‐(2.2‐Dibromovinyl)aniline ando‐Ethynylaniline

Abstract A Pd‐catalyzed coupling reaction from o ‐alkynylanilines and o ‐(2,2‐dibromovinyl)anilines for the synthesis of 2,3′‐bisindoles is developed. In which, o ‐ethynylaniline was used as 3‐functionalized indole precursor and o ‐(2,2‐dibromovinyl)aniline was used as 2‐functionalized indole precursor. This protocol exhibits high efficiency, good functional group tolerance and scalability from easily accessible starting materials.