代谢组学
败血症
微生物群
医学
精密医学
主机响应
危重病
计算生物学
重症监护医学
基因组学
机制(生物学)
疾病
生物信息学
病危
免疫学
生物
基因组
内科学
病理
遗传学
免疫系统
哲学
认识论
基因
作者
Jisoo Lee,Debasree Banerjee
标识
DOI:10.1016/j.ccc.2019.08.008
摘要
Metabolomics is an emerging field of research interest in sepsis. Metabolomics provides new ways of exploring the diagnosis, mechanism, and prognosis of sepsis. Advancements in technologies have enabled significant improvements in identifying novel biomarkers associated with the disease progress of sepsis. The use of metabolomics in the critically ill may provide new approaches to enable precision medicine. Furthermore, the dynamic interactions of the host and its microbiome can lead to further progression of sepsis. Understanding these interactions and the changes in the host’s genomics and the microbiome can provide novel preventive and therapeutic strategies against sepsis.
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