Objective:To prevent or reduce the puncture point bleeding,we evaluate the method of radial compression guided by standard compression with a pneumatic device (TR Band).Methods:360 patients under a coronary angiography by transradial access for PCI were divided into 2 groups randomly:common control group (using TR Band,n=160),(using TR Band and gauze,n=160).Results:An analysis of the results of 160 patients in experimental group showed significantly (P 0.05) lower incidence of bleeding and infection than common control group with 160 patients.Conclusion:Use of pneumatic compression guided by TR Band and gauze is safe and efficient,and it can significantly lower the incidence of radial artery bleeding and infection.