Self-assembly peptide tissue engineering scaffold is a novel nano scaffold consisting of complementary amphiphilic oligopeptide which have self-assembly character.The nano microstructure of this kind of scaffold is similar to the natural extracellular matrix and this character makes it to be a genuine three dimensional cell culture scaffold.Therefore,this kind of scaffold has some incomparable advantages and characters with other scaffolds.The next context makes a review about the structure,character and application of the self-assembly peptide tissue engineering scaffold.