Impacts of Ca~(2+) in sperm capacitation and acrosome reaction

Capacitation and acrosome reaction is an important process in sperm maturation and in fertilization. Although capacitation and acrosome reaction are now considered to be mediated by intracellular signaling events, including protein phosphorglation, the regulation of the transduction mechamisms is poorly understood. This paper illustrite the importance of Ca2+ and its effect in capacitation and acrosome reaction.