Zebras Seize the Day

Status epilepticus (SE) is a common neurologic emergency and is associated with a high risk of morbidity and mortality. The management of SE in the intensive care unit centers on stabilization and treatment, as well as identifying and treating the underlying etiology. Numerous etiologies of SE are amenable to treatment, including certain genetic and metabolic disorders, autoimmune encephalitis and other inflammatory disorders, intracranial infections, and toxic/metabolic derangements. This article highlights rare but important causes of SE across the continuum of care from neonates to adults.