Synthesis of Functionalized Isoquinolin‐1(2H)‐ones by Copper‐Catalyzed α‐Arylation of Ketones with 2‐Halobenzamides

Copper is key: A concise route to isoquinolin-1(2H)-ones from simple and readily available starting materials is provided by an efficient copper-catalyzed annulation of ketones with 2-halobenzamides. The method is applicable to a wide range of ketones containing different functional groups furnishing the products in moderate to excellent yields.