医学
肥胖
2型糖尿病
内科学
自杀意念
保证
儿科
梅德林
糖尿病
青少年肥胖
临床试验
体力活动
作者
Pareeta Kotecha,Wenxi Huang,Ya-Yun Yeh,Vincent Narvaez,Darlene Adirika,Huilin Tang,Angelina Bernier,Sarah Westen,Steven M. Smith,Jiang Bian,Jingchuan Guo
出处
期刊:JAMA Pediatrics
[American Medical Association]
日期:2025-09-15
卷期号:179 (12): 1308-1308
被引量:7
标识
DOI:10.1001/jamapediatrics.2025.3243
摘要
In this systematic review and meta-analysis of 18 trials, GLP-1 RAs significantly improved glycemic, weight, and cardiometabolic outcomes in children and adolescents with T2D or obesity. Available data over a relatively short follow-up suggested suicidal ideation or behaviors were not significantly different, although GI AEs warrant attention in long-term management.
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