吲哚青绿
乳腺癌
共轭体系
超顺磁性
医学
放射科
癌症
材料科学
内科学
病理
聚合物
磁化
量子力学
磁场
物理
复合材料
作者
Cheng‐Ta Yang,Kunli Liu,Cheng‐You Yao,Bo Li,Aniwat Juhong,Zhen Qiu,Xuefei Huang
出处
期刊:ACS applied nano materials
[American Chemical Society]
日期:2022-12-05
卷期号:5 (12): 18912-18920
被引量:3
标识
DOI:10.1021/acsanm.2c04687
摘要
Breast cancer is the leading cause of cancer-associated deaths among women. Techniques for non-invasive breast cancer detection and imaging are urgently needed. Multimodality breast cancer imaging is attractive since it can integrate advantages from several modalities, enabling more accurate cancer detection. In order to accomplish this, indocyanine green (ICG)-conjugated superparamagnetic iron oxide nanoworm (NW-ICG) has been synthesized as a contrast agent. When evaluated in a spontaneous mouse breast cancer model, NW-ICG gave a large tumor to normal tissue contrasts in multiple imaging modalities including magnetic particle imaging, near-infrared fluorescence imaging, and photoacoustic imaging, providing more comprehensive detection and imaging of breast cancer. Thus, NW-ICGs are an attractive platform for non-invasive breast cancer diagnosis.
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