Huatan Jiangqi Capsule in Treating Experimental Chronic Bronchitis:A Histopathologic Study

Objective:To initially observe therapeutic effects of Huatan Jiangqi(HTJQ) Capsule in treating experimental chronic bronchitis in rats.Methods: Rats were randomized into high-,middle-and low-dosage of HTJQ Capsule groups(0.140,0.070,0.035 g/ml,respectively),Guilong Kechuan Ning(GLKCN) Capsule group and sham operation group.The rat model of chronic bronchitis was induced by injecting lipopolysaccharide.The histopathologic changes of rats in all groups were observed under light microscope.Results: The histopathologic conditions of rats in HTJQ Capsule groups were markedly improved.HTJQ Capsule could relieve the amotio of ciliated epithelium;decrease the accrementition of caliciform cells and the infiltrating of inflammatory cells.The effects of high-dosage of HTJQ Capsule were superior to those of middle-and low-dosage of HTJQ Capsule.Conclusion: HTJQ Capsule possesses therapeutic effects on experimental chronic bronchitis in rats.