Flexible and low-cost organic bioelectronics devices, as described by L. Li, F. Yan, and co-workers on page 7493, have emerged as a versatile platform for various biological applications, such as DNA, cells, proteins, and neuron signal monitoring. The integration of organic devices with biomaterials can synergize the two naturally compatible systems and create technological opportunities that are not possible with conventional inorganic devices, promising a bright future for this emerging area.