安普克
脂肪生成
脂肪变性
内科学
内分泌学
丁酸钠
丁酸盐
脂质代谢
非酒精性脂肪肝
AMP活化蛋白激酶
乙酰辅酶A羧化酶
生物
胰岛素
蛋白激酶A
脂肪肝
医学
激酶
细胞生物学
生物化学
丙酮酸羧化酶
疾病
基因
发酵
酶
作者
Zehua Zhao,Zixuan Wang,Da Zhou,Yamei Han,Fengguang Ma,Zhimin Hu,Feng‐Zhi Xin,Xiaolin Liu,Tianyi Ren,Feifei Zhang,Yaqian Xue,Aoyuan Cui,Zhengshuai Liu,Jinyun Bai,Yuxiao Liu,Genxiang Cai,Weitong Su,Xiaozhen Dai,Feng Shen,Qin Pan
标识
DOI：10.1016/j.jcmgh.2021.05.006
摘要
These studies indicate that NaB serves as a negative regulator of hepatic lipogenesis in NAFLD and that NaB attenuates hepatic steatosis and improves lipid profile and liver function largely through the activation of LKB1-AMPK-Insig signaling pathway. Therefore, NaB has therapeutic potential for treating NAFLD and related metabolic diseases.
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(2025-6-4)
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