Synthesis of (±)‐12‐Methoxyherbertenediol Dimethyl Ether

Abstract Efficient total synthesis of (±)‐12‐methoxyherbertenediol dimethyl ether and 12‐homoherbertenediol was accomplished starting from vanillin employing a Claisen rearrangement–RCM reaction–based approach. Keywords: metathesisnatural productsrearrangementring closuretotal synthesis Acknowledgments We thank G. Nagaraju for checking the reproducibility of some of the reactions. Two of us (S. R. K. and P. C. R.) thank Council of Scientific and industrial Research (CSIR), New Delhi, for the award of research fellowships.