The Effect Of Traditional Chinese Exercise On early Diabetic Nephropathy

PURPOSE: It was reported that early diabetic nephropathy (DN) is associated with sedentary lifestyle, and proper exercise can improve its symptoms and prognosis. However, limited data evaluated the effects and safety of traditional Chinese exercise in patients with early DN. This study was aimed at observing the effects and safety of traditional Chinese exercise on early DN. METHODS: Participants (n=21) were divided into the traditional Chinese exercise group (A group, n=12) and the control group (B group, n=9) for 12 weeks. On the basis of foundation treatment, group A was given the exercise 30 minutes per day, 4 times a week while no exercise intervention was given in group B. Fasting blood glucose, glycated hemoglobin (HbA1c), serum creatinine, urea, and the MUNSH scale were taken at baseline and 12 weeks later. RESULTS: 1) Significant differences were found in group A in HbA1c (6.90±0.92 vs 6.43±0.78, P < 0.05), BMI (26.30±3.49 vs 25.83±3.06, P < 0.05) and VO2peak (15.43±1.49 vs 16.14±1.89, P < 0.05) compared with group B (Ps > 0.05). The differences of MUNSH scale were significantly greater: positive emotion (6.75±3.14 vs 7.92±2.97, P < 0.01), positive experience (8.08±4.03 vs 10.00±3.77, P < 0.05), total score (32.67±11.28 vs 38.33±12.27, P < 0.01). 2) No adverse reactions were observed during the trail. Few changes were found in renal function and urinary protein in two groups (P > 0.05). CONCLUSIONS: Traditional Chinese exercise therapy was safe and effective in treating early DN patients. It also has effects on improving the physical and mental health. Supported by JDZX2015136