Secondary metabolites from an endophytic fungus Trichoderma erinaceum with antimicrobial activity towards Pythium ultimum

Chemical investigation of the endophytic fungus, Trichoderma erinaceum, isolated from healthy and asymptomatic common bean field crop, resulted in the isolation of a new alkene, (Z)-5-amino-5-(1,1,2-trihydroxybuta-1,3-dienyloxy)pentane-6,7,8,9-tetraol (1), together with five known compounds (2-6). The structures of the compounds were elucidated by analysis of their spectroscopic data including 1 D, 2 D NMR, ESI-HRMS and literature data. The organic crude extract and the compound isolated from T. erinaceum significantly (p ≤ 0.05) inhibited the mycelial growth of Pythium ultimum.