SiO2 templates-derived hierarchical porous COFs sample pretreatment tool for non-targeted analysis of chemicals in foods

• A simple method is developed for the facile preparation of highly hierarchical COFs. • HCOFs have interconnected channels and thus fully exposed interior pores. • HCOFs are demonstrated to work well for ultrafast (in 3 s) sample pretreatment. • HCOFs are successfully used for the non-targeted analysis of 90 chemical hazards from 6 foods. • This work pave a new way to remodel COFs and improve the applications of COFs in many fields.