胶质瘤
免疫系统
免疫逃逸
癌症研究
生物
病理
医学
免疫学
作者
Patrick Roth,Markus Junker,Isabel Tritschler,Michel Mittelbronn,Yvonne Dombrowski,Samuel N. Breit,Ghazaleh Tabatabai,Wolfgang Wick,Michael Weller,Jörg Wischhusen
标识
DOI：10.1158/1078-0432.ccr-10-0705
摘要
Although previous studies focusing on ectopic overexpression of GDF-15 have proposed unclear or antitumorigenic effects of GDF-15 in glioma cells, we here show that GDF-15 at endogenous levels contributes to proliferation and immune escape of malignant gliomas in an immunocompetent host.
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(2025-6-4)
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