Significance of MRI on Living Animals Treated by Liver Cancer DC Vaccine

Objective:To analyze the significance of MRI on living animals treated by liver cancer DC vaccine and evaluate the effect of liver cancer DC vaccine on cases with liver cancer.Methods:Rabbit liver cancer animal model(n=40) was established.The research group(n=30) was treated by liver cancer DC vaccine.The control group(n=10) was not treated by DC vaccine.The size of the tumor,form and signal change were observed through MRI.Results:Inoculation with tumor for 14 days later,cancer detection rate was 94.44 %(34/36),and all lesions were displayed by enhancement scan.After DC vaccine injection,the tumor volume was not enlarged,and some tumor shrunk,no spread and metastasis.But there were no significant difference in different injection ways.The tumor volume was still enlarged and tumor wall increased unequally after inoculated tumor for 21 days.Some tumors appeared liver or lung shift,T2 signal increased.Conclusion:MRI on living animals treated by liver cancer DC vaccine has the vital significance.