Through observing the air quality in four city monitor station of Nanning from 5th to 12th November,2012,the concentration change of particulate pollutant,PM10 and PM2.5,and the concentration of main composition of PM2.5 were analyzed.The meteorological condition during air pollution was analyzed based on meteorological data from Guangxi Meteorological Service Center.The results showed that during the air pollution period,the concentration particulate pollutant as the major cause of the air pollution,increased significantly.OM and Sulfate are the main components of PM2.5 at that time.The meteorological factors play an important role in the air pollution.Air came from Hunan direction also played a certain role in long time air pollution.