医学
转移
骨转移
癌症
内科学
肿瘤科
化疗
骨痛
原发性肿瘤
胃肠病学
胃切除术
作者
Tsuyoshi Etoh,Hideo Baba,Akinobu Taketomi,Hideaki Nakashima,Shunji Kohnoe,Seo Y,Takao Saito,Hirotsugu Tomoda
摘要
We herein present a case of diffuse bone metastasis from early gastric cancer with disseminated intravascular coagulation (DIC) in a 40-year old man, who had undergone a curative gastrectomy and had no evidence of recurrence for five years after surgery. The patient was treated with an intravenous administration of sequential methothrexate (MTX) and 5-fluorouracil (5-FU), and demonstrated a favorable clinical course without any severe pain. Despite the fact that the presence of diffuse bone metastasis from gastric cancer plus hematologic disorders tends to indicate a significantly poor prognosis, the patient survived for a relatively long period (11 months) following chemotherapy. We thus conclude that MTX/5-FU sequential therapy seems to be a clinically useful regimen to improve both the symptoms and survival for cases of diffuse bone metastasis from gastric cancer.
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