博思罗普
蛇毒
组胺
毒液
肥大细胞
凝集素
血管通透性
免疫学
药理学
生物
化学
生物化学
内分泌学
作者
Fábio Henrique Kwasniewski,Anderson M. Kayano,Ariane N. Fukunaga,Sulamita da Silva Setúbal,Andreimar Martins Soares,Juliana Pavan Zuliani
出处
期刊:Toxicon
[Elsevier]
日期:2022-01-01
卷期号:205: 20-23
被引量:2
标识
DOI:10.1016/j.toxicon.2021.11.006
摘要
Bothrops species trigger an acute inflammatory response in victims, with activated leukocytes releasing several mediators that may contribute to local and systemic effects. The effects of BjcuL, a lectin isolated from B. jararacussu snake venom, on mast cells and vasopermeability were investigated in this study. BjcuL activates mast cells and increases vasopermeability through the involvement of histamine and platelet activating factor, which may play a role in the victims' acute inflammatory reaction.
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