A Simple Approach for 3D IVUS‐Angiographic Co‐Registration for CTOs Using the “Be‐The‐Wire” Cognitive Model

ABSTRACT Percutaneous coronary intervention (PCI) for chronic total occlusions (CTO) is a technically demanding procedure where successful guidewire navigation is critical. While intravascular ultrasound (IVUS) provides essential anatomical detail, its utility is often limited by the cognitive challenge of correlating the 2D IVUS image with the 3D angiographic view. A failure in this co‐registration can lead to procedural failure. To address this challenge, we detail the “Be‐The‐Wire” cognitive model, a simple, six‐step mnemonic‐based method for achieving intuitive 3D IVUS‐angiographic co‐registration. The technique requires the operator to adopt the perspective of being the IVUS‐carrying wire, with their head positioned on the proximal side of the coronary artery. Key steps include optimizing the angiographic view for gear separation, deducing the C‐arm's viewing angle, mapping this angle to a clock‐face position on the IVUS display, and physically rotating the screen to align it with the vessel's trajectory. The “Be‐The‐Wire” cognitive model provides a simple yet profound method to improve guidewire control by facilitating intuitive co‐registration without requiring complex software. Mastering this technique is a valuable step which may potentially contribute to improving safety and success rates in complex CTO PCI.