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Trends in Nanomedicines for Cancer Treatment

纳米载体 纳米医学 癌症治疗 医学 脂质体 癌症治疗 纳米技术 癌症 放射治疗 药理学 药品 纳米颗粒 材料科学 内科学 外科
作者
Tatielle do Nascimento,Adriane R. Todeschini,Ralph Santos‐Oliveira,Mariana Sato de Souza de Bustamante Monteiro,Vilênia Toledo de Souza,Eduardo Ricci‐Júnior
出处
期刊:Current Pharmaceutical Design [Bentham Science Publishers]
卷期号:26 (29): 3579-3600 被引量:10
标识
DOI:10.2174/1381612826666200318145349
摘要

Cancer is characterized by abnormal cell growth and considered one of the leading causes of death around the world. Pharmaceutical Nanotechnology has been extensively studied for the optimization of cancer treatment.Comprehend the panorama of Pharmaceutical Nanotechnology in cancer treatment, through a survey about nanomedicines applied in clinical studies, approved for use and patented.Acknowledged products under clinical study and nanomedicines commercialized found in scientific articles through research on the following databases: Pubmed, Science Direct, Scielo and Lilacs. Derwent tool was used for patent research.Nanomedicines based on nanoparticles, polymer micelles, liposomes, dendrimers and nanoemulsions were studied, along with cancer therapies such as Photodynamic Therapy, Infrared Phototherapy Hyperthermia, Magnetic Hyperthermia, Radiotherapy, Gene Therapy and Nanoimmunotherapy. Great advancement has been observed over nanotechnology applied to cancer treatment, mainly for nanoparticles and liposomes.The combination of drugs in nanosystems helps to increase efficacy and decrease toxicity. Based on the results encountered, nanoparticles and liposomes were the most commonly used nanocarriers for drug encapsulation. In addition, although few nanomedicines are commercially available, this specific research field is continuously growing.
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