High‐toughness Spider Silk Fibers Spun from Soluble Recombinant Silk Produced in Mammalian Cells

Abstract Introduction Historical Outline Production of rc‐Spider Silk Proteins Over‐expression of Soluble rc‐Spider silk Proteins in Mammalian Cells Secretion of rc‐Dragline Spider Silk proteins Large‐scale Production of rc‐Spider Silk Proteins Purification and Characterization of rc‐Spider Silk Proteins Production of rc‐Spider Silk Proteins in the Milk of Transgenic Animals Generation of Transgenic Mice for the Spider Dragline Silk Genes Mammary Gland Production of Spider Dragline Silk Proteins Recombinant Spider Silk‐based Fiber Spinning Spin Dope Preparation, Fiber Spinning and Characterization Fiber Post‐Spinning Treatment Perspective on the Formation of Silk Fibers and the Spinning Process Applications of rc‐Spider Silk Fibers, and Prospects Patents Chronological Summary of Patents Conclusions Acknowledgments