材料科学
电阻抗
电极
生物医学工程
脑电图
微加工
角质层
帕利烯
渗透(战争)
计算机科学
光电子学
纳米技术
复合材料
电气工程
化学
制作
工程类
病理
物理化学
医学
运筹学
替代医学
聚合物
精神科
心理学
作者
Renxin Wang,Xiaoming Jiang,Wei Wang,Zhihong Li
标识
DOI:10.1016/j.snb.2017.01.052
摘要
Conventional wet electrodes require skin preparation and gel usage to maintain low interface impedance, which limit their applications in long-term monitoring of biopotentials such as electroencephalogram (EEG). To address this problem, microneedle electrode arrays (MNEAs) have been employed as dry electrodes, which could be capable of EEG monitoring without skin abrasion and gel electrolyte. However, most of them are usually based on rigid substrates that are not conformal to curved and moved human skin. Therefore, we develop a flexible parylene-based MNEA (P-MNEA) with silicon microneedles, which could provide not only conformal but also robust contact. Firstly, the microfabrication process is concretely illustrated and makes it repeatable. Then, penetration tests illustrate these microneedles are robust enough to penetrate into epidermis so that impedances of stratum corneum make limited contribution to interface impedance. Consequently, in vivo impedance results verify the priority of P-MNEA in long-time impedance stability. Meanwhile, competitive impedance density of 7.5 KΩ cm2@10 Hz is attained. Eventually, EEG recoding results as well as correlation and coherence analyses of P-MNEA indicate comparable performance to that of wet electrode. In brief, these results reveal promising prospect of P-MNEA in long-time EEG monitoring.
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