Fall history and risk of incident stroke in middle-aged and older adults with possible sarcopenia: A longitudinal cohort study based on CHARLS

Fall history independently predicts stroke risk in individuals with PS, highlighting the potential of fall prevention to reduce stroke burden in this population. This study provides novel evidence of a prolonged stroke risk trajectory in Asian PS cohorts, complementing Western studies focused on short-term post-fall risks. The study has several limitations. Self-reported falls may introduce recall bias and lack mechanistic details. Unmeasured confounders such as diet and medication use constrain causal interpretation. Data constraints prevented differentiation between stroke subtypes.