医学
哮喘
疾病
个性化医疗
精密医学
重症监护医学
哮喘管理
透视图(图形)
替代医学
医疗保健
临床实习
生物信息学
家庭医学
免疫学
病理
人工智能
计算机科学
经济
生物
经济增长
作者
Amir Bahmani,Mahmoud I. Abdel‐Aziz,Anke H. Maitland‐van der Zee,Susanne Vijverberg
标识
DOI:10.1080/17512433.2022.2131537
摘要
Introduction Childhood asthma is a complex heterogenous inflammatory disease that can pose a large burden on patients and their caregivers. There is a strong need to adapt asthma treatment to the individual patient taking into account underlying inflammatory profiles, moving from a ‘one size fits all’ approach toward a much-needed personalized approach.Areas covered This review article aims to provide an overview of recent advances in the management and treatment of pediatric asthma, including novel insights on the molecular heterogeneity of childhood asthma, the emergence of biologicals to treat severe asthma, and innovative e-health and home monitoring techniques to make asthma management more convenient and accessible.Expert opinion Molecular technologies have provided new treatment leads. E-health and home monitoring technologies have helped to gain more insights into disease dynamics and improve adherence to treatment while bringing health care to the patient. However, uncontrolled childhood asthma is still a major unmet clinical need and precision-medicine approaches are still scarce in clinical practice. Advanced omics methods may help researchers or clinicians to more accurately phenotype and treat subtypes of childhood asthma and gain more insight into the complexity of the disease.
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