黑色素瘤
组织微阵列
黑素皮质素1受体
医学
免疫组织化学
肿瘤科
转移
生物标志物
内科学
病理
癌症
癌症研究
表型
生物
生物化学
基因
作者
David Su,Dijana Djureinovic,David A. Schoenfeld,Bernadette Marquez‐Nostra,Kelly Olino,Lucia B. Jilaveanu,Harriet M. Kluger
摘要
Melanocortin-1 receptor (MC1R) plays a critical role in human pigmentation and DNA repair mechanisms. MC1R-targeting agents are being investigated in clinical trials in patients with melanoma, yet large studies investigating the rate and degree of MC1R expression in primary and metastatic human melanoma tissue are lacking.
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