Blau syndrome presenting as lipoma arborescens

A 29-year-old woman presented with a 23-year history of multiple joint swelling and intermittent pain. Physical examination showed large, soft, and fluctuant soft tissue swelling of the hands, wrists, elbows, knees, and ankles, bilaterally (figure A; appendix p 2). Symmetric tense knee effusions restricted her range of motion. She had previously had multiple recurrences of panuveitis, cataract, and secondary glaucoma in both eyes for 7 years, with retinal detachment leading to blindness in her left eye.