Prioritizing endocrine-disrupting chemicals targeting systemic lupus erythematosus genes via Mendelian randomization and colocalization analyses

This study highlights the complex interactions between EDCs and genetic predisposition in SLE. The findings provide valuable insights into how environmental exposures, particularly EDCs, may contribute to the development and progression of autoimmune diseases like SLE. These results suggest potential targets for future therapeutic interventions and underscore the need for further research on gene-environment interactions in SLE.