Discovery and heterologous biosynthesis of glycosylated polyketide luteodienoside A reveals unprecedented glucinol-mediated product offloading by a fungal carnitine O-acyltransferase domain

Luteodienoside A – a glycosylated polyketide produced by the Australian fungus Aspergillus luteorubrus is biosynthesised by a polyketide synthase with a carnitine O -acyltransferase domain capable of adding glucinol to the polyketide product.