Raddeanin A Improves the Therapeutic Effect of Osimertinib in NSCLC byAccelerating ROS/NLRP3-mediated Pyroptosis

RA inhibited the NSCLC growth and increased the anti-tumor role of Osm in NSCLC by facilitating ROS/NLRP3-mediated pyroptosis. These results suggested that combination therapy with RA and Osm might be an effective strategy to treat Osm-resistant NSCLC.