脂肪组织
干细胞
间充质干细胞
干细胞移植修复关节软骨
成体干细胞
细胞生物学
神经干细胞
生物
病理
体外
内皮干细胞
医学
内分泌学
生物化学
作者
Barbara Zavan,Vindigni,Chiara Gardin,Domenico D’Avella,Alessandro Della Puppa,Giovanni Abatangelo,Roberta Cortivo
出处
期刊:PubMed
日期:2010-07-01
卷期号:10 (50): 37-43
被引量:15
摘要
In the last few years, adipose tissue, which has been largely ignored by anatomists and physicians for centuries, has found new brightness thanks to the stem cells contained within. These adipose derived stem cells (ADSC) have the same characteristics of the mesenchymal stem cells (MSC) residing in bone marrow. They have the same cell surface markers and are capable of differentiating into the same cell types, including osteoblasts, chondrocytes, myoblasts, adipocytes, and neuron-like cells. Adipose tissue is ubiquitous and uniquely expandable. Most patients possess excess fat that can be harvested, making adipose tissue the ideal large-scale source for research on clinical applications. In this review focused on the neural potential of adipose-derived stem cells. Current strategies for their isolation, differentiation, and in vitro characterization, as well as their latest in vivo applications for neurological disorders or injury repair, were discussed.
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