Neonatal guideline hypoxic-ischemic encephalopathy (HIE).

Hypoxic ischemic cerebral injury that occurs during the perinatal period is one of the most commonly recognized causes of severe, long-term neurological deficits in children, often referred to as cerebral palsy. Until recently, current management strategies have largely been supportive and not targeted toward the processes of ongoing injury. Hypothermia is a novel, exciting strategy that offers an opportunity for neuroprotection.