头颈部鳞状细胞癌
医学
头颈部癌
槟榔
基底细胞
肿瘤科
鳞状细胞癌
头颈部
槟榔
癌症
内科学
癌症研究
外科
螺母
结构工程
工程类
作者
Cristina Porcheri,Thimios A. Mitsiadis
出处
期刊:Cancers
[MDPI AG]
日期:2021-11-03
卷期号:13 (21): 5515-5515
被引量:11
标识
DOI:10.3390/cancers13215515
摘要
Head and neck squamous cell carcinoma (HNSCC) is one of the most frequent types of cancer with a lethal outcome in half of the diagnosed cases. Mostly, HNSCC develops in the oral cavity, and its development is associated with tobacco and areca nut/betel quid usage, alcohol consumption, and HPV infection. Oral squamous cell carcinoma, as other head and neck cancers, presents a high degree of intratumor heterogeneity, which makes their treatment difficult, and directly correlates with drug resistance. Since the classical treatments for HNSCC oftentimes do not resolve the clinical picture, there is great need for novel therapeutic approaches, models for drug testing, and new drug delivery systems.
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