Total knee arthroplasty improves both knee function and disease activity in patients with rheumatoid arthritis

This study evaluated the effect of TKA with capsulosynovectomy on disease activity and knee function in patients with RA.Seventy-six RA patients who underwent primary TKA with more than two years of follow-up were retrospectively reviewed to assess postoperative knee function and disease activity.Postoperative knee function was significantly improved in all clinical scores, and maintained up to 24 months after surgery. RA disease activity was significantly decreased in DAS28-CRP, CDAI, and serum CRP level, and maintained up to 24 months after surgery. Postoperative knee function was negatively correlated with RA disease activity.TKA improves both knee function and disease activity in patients with rheumatoid arthritis.