超分子化学
哒嗪
折叠(DSP实现)
结晶学
分子间力
自组装
化学
超分子组装
立体化学
分子
材料科学
纳米技术
晶体结构
有机化学
电气工程
工程类
作者
Louis A. Cuccia,Eliseo Ruiz,Jean‐Marie Lehn,Jean-Claude Homo,Marc Schmutz
标识
DOI:10.1002/1521-3765(20020802)8:15<3448::aid-chem3448>3.0.co;2-
摘要
The synthesis and characterization of an alternating pyridine-pyridazine strand comprising thirteen heterocycles are described. Spontaneous folding into a helical secondary structure is based on a general molecular self-organization process enforced by the conformational information encoded within the primary structure of the molecular strand itself. Conformational control based on heterocyclic "helicity codons" illustrates a strategy for designing folding properties into synthetic oligomers (foldamers). Strong intermolecular interactions of the highly ordered lock-washer subunits of compound 3 results in hierarchical supramolecular self-assembly into protofibrils and fibrils. Compound 3 also forms mechanically stable two-dimensional Langmuir-Blodgett and cast thin films.
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