对映选择合成
丙二酸
氰胺
化学
功能群
有机化学
药物化学
催化作用
聚合物
作者
Yusuke Oyamada,Kazuto Inaba,Takahiro Sasamori,Shuichi Nakamura
摘要
The enantioselective reaction of imines bearing a cyano group as an activating group with malonic acid half thioesters gave chiral cyanamide derivatives with high enantioselectivity. The density functional theory (DFT) calculation clarified the stereochemical outcome and importance of the N-cyano group for imines.
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